Как искать в интернете достоверную медицинскую информацию

Alternative interfaces

MEDLINE is one of the databases which are accessible via PubMed. Several companies provide access to MEDLINE through their platforms.

The National Library of Medicine leases the MEDLINE information to a number of private vendors such as Embase, Ovid, Dialog, EBSCO, Knowledge Finder and many other commercial, non-commercial, and academic providers. As of October 2008, more than 500 licenses had been issued, more than 200 of them to providers outside the United States. As licenses to use MEDLINE data are available for free, the NLM in effect provides a free testing ground for a wide range of alternative interfaces and 3rd party additions to PubMed, one of a very few large, professionally curated databases which offers this option.

Lu identifies a sample of 28 current and free Web-based PubMed versions, requiring no installation or registration, which are grouped into four categories:

Ranking search results, for instance: eTBLAST; MedlineRanker; MiSearch;
Clustering results by topics, authors, journals etc., for instance: Anne O’Tate; ClusterMed;
Enhancing semantics and visualization, for instance: EBIMed; MedEvi.
Improved search interface and retrieval experience, for instance, askMEDLINE BabelMeSH; and PubCrawler.

Cited by 9 articles

Глюкометр ай чек
Hepatoblastoma: current knowledge and promises from preclinical studies.

Calvisi DF, Solinas A.
Calvisi DF, et al.
Transl Gastroenterol Hepatol. 2020 Jul 5;5:42. doi: 10.21037/tgh.2019.12.03. eCollection 2020.
Transl Gastroenterol Hepatol. 2020.

PMID: 32632393
Free PMC article.

Review.
Application of photodynamic therapy for liver malignancies.

Zou H, Wang F, Zhou JJ, Liu X, He Q, Wang C, Zheng YW, Wen Y, Xiong L.
Zou H, et al.
J Gastrointest Oncol. 2020 Apr;11(2):431-442. doi: 10.21037/jgo.2020.02.10.
J Gastrointest Oncol. 2020.

PMID: 32399283
Free PMC article.

Review.
LIN28B gene polymorphisms modify hepatoblastoma susceptibility in Chinese children.

Yang Z, Deng Y, Zhang K, Bai Y, Zhu J, Zhang J, Xin Y, Li L, He J, Wang W.
Yang Z, et al.
J Cancer. 2020 Mar 15;11(12):3512-3518. doi: 10.7150/jca.42798. eCollection 2020.
J Cancer. 2020.

PMID: 32284747
Free PMC article.
HMGA2 Polymorphisms and Hepatoblastoma Susceptibility: A Five-Center Case-Control Study.

Li L, Zhuo Z, Yang Z, Zhu J, He X, Yang Z, Zhang J, Xin Y, He J, Zhang T.
Li L, et al.
Pharmgenomics Pers Med. 2020 Feb 11;13:51-57. doi: 10.2147/PGPM.S241100. eCollection 2020.
Pharmgenomics Pers Med. 2020.

PMID: 32104047
Free PMC article.
m6A mRNA methylation regulates CTNNB1 to promote the proliferation of hepatoblastoma.

Liu L, Wang J, Sun G, Wu Q, Ma J, Zhang X, Huang N, Bian Z, Gu S, Xu M, Yin M, Sun F, Pan Q.
Liu L, et al.
Mol Cancer. 2019 Dec 23;18(1):188. doi: 10.1186/s12943-019-1119-7.
Mol Cancer. 2019.

PMID: 31870368
Free PMC article.

Data mining of PubMed

Интернист

Alternative methods to mine the data in PubMed use programming environments such as Matlab, Python or R. In these cases, queries of PubMed are written as lines of code and passed to PubMed and the response is then processed directly in the programming environment. Code can be automated to systematically queries with different keywords such as disease, year, organs, etc. A recent publication (2017) found that the proportion of cancer-related entries in PubMed has risen from 6% in the 1950s to 16% in 2016.

The data accessible by PubMed can be mirrored locally using an unofficial tool such as MEDOC.

Millions of PubMed records augment various open data datasets about open access, like Unpaywall. Data analysis tools like Unpaywall Journals are used by libraries to assist with big deal cancellations: libraries can avoid subscriptions for materials already served by instant open access via open archives like PubMed Central.

What’s New

Visit our What’s New page to see all recent MeSH developments including the most recent ones listed below

2020 MeSH files are now in production
- The MeSH Browser now displays 2020 MeSH and 2019 MeSH vocabularies
- Reports of MeSH changes are available from our What’s New page
- All 2020 MeSH files are now available via FTP download
MeSH in Resource Description Format(RDF) is now in production
- The downloadable files contain a full representation of XML MeSH in RDF format
- An open MeSH API is available for retrieving MeSH data
- You can use our SPARQL query editor for querying MeSH data

MeSH on Demand 2.0 has been re-engineered and improved in response to your suggestions.
- Matching MeSH terms are now highlighted in response to your submitted text
- MeSH headings now include links to scope notes
- Custom PubMed searches are more easily made
- Term expansion and tree-based searching features have been added
- You can now display of similar article titles from PubMed

Cited by 8 articles

Adolescent Dietary Habit-induced Obstetric and Gynecologic Disease (ADHOGD) as a New Hypothesis-Possible Involvement of Clock System.

Fujiwara T, Ono M, Mieda M, Yoshikawa H, Nakata R, Daikoku T, Sekizuka-Kagami N, Maida Y, Ando H, Fujiwara H.
Fujiwara T, et al.
Nutrients. 2020 May 2;12(5):1294. doi: 10.3390/nu12051294.
Nutrients. 2020.

PMID: 32370105
Free PMC article.
The Effect of a High-Fat Diet on the Fatty Acid Composition in the Hearts of Mice.

Pakiet A, Jakubiak A, Mierzejewska P, Zwara A, Liakh I, Sledzinski T, Mika A.
Pakiet A, et al.
Nutrients. 2020 Mar 20;12(3):824. doi: 10.3390/nu12030824.
Nutrients. 2020.

PMID: 32245049
Free PMC article.
Role of environmental factors & oxidative stress with respect to in vitro fertilization outcome.

Kumar S, Mishra V, Thaker R, Gor M, Perumal S, Joshi P, Sheth H, Shaikh I, Gautam AK, Verma Y.
Kumar S, et al.
Indian J Med Res. 2018 Dec;148(Suppl):S125-S133. doi: 10.4103/ijmr.IJMR_1864_17.
Indian J Med Res. 2018.

PMID: 30964090
Free PMC article.
Time Restriction of Food Intake During the Circadian Cycle Is a Possible Regulator of Reproductive Function in Postadolescent Female Rats.

Fujiwara T, Nakata R, Ono M, Mieda M, Ando H, Daikoku T, Fujiwara H.
Fujiwara T, et al.
Curr Dev Nutr. 2018 Nov 26;3(4):nzy093. doi: 10.1093/cdn/nzy093. eCollection 2019 Apr.
Curr Dev Nutr. 2018.

PMID: 30963143
Free PMC article.
Epidemiologic Factors Associated with Endometriosis in East Asia.

Yen CF, Kim MR, Lee CL.
Yen CF, et al.
Gynecol Minim Invasive Ther. 2019 Jan-Mar;8(1):4-11. doi: 10.4103/GMIT.GMIT_83_18. Epub 2019 Jan 23.
Gynecol Minim Invasive Ther. 2019.

PMID: 30783582
Free PMC article.

Review.

Content

In addition to MEDLINE, PubMed provides access to:

older references from the print version of Index Medicus, back to 1951 and earlier
references to some journals before they were indexed in Index Medicus and MEDLINE, for instance Science, BMJ, and Annals of Surgery
very recent entries to records for an article before it is indexed with Medical Subject Headings (MeSH) and added to MEDLINE
a collection of books available full-text and other subsets of NLM records
PMC citations

Many PubMed records contain links to full text articles, some of which are freely available, often in PubMed Central and local mirrors, such as Europe PubMed Central.

Information about the journals indexed in MEDLINE, and available through PubMed, is found in the NLM Catalog.

As of 27 January 2020, PubMed has more than 30 million citations and abstracts dating back to 1966, selectively to the year 1865, and very selectively to 1809. As of the same date, 20 million of PubMed’s records are listed with their abstracts, and 21.5 million records have links to full-text versions (of which 7.5 million articles are available, full-text for free). Over the last 10 years (ending 31 December 2019), an average of nearly 1 million new records were added each year. Approximately 12% of the records in PubMed correspond to cancer-related entries, which have grown from 6% in the 1950s to 16% in 2016.
Other significant proportion of records correspond to «chemistry» (8.69%), «therapy» (8.39%), and «infection» (5%).[citation needed]

In 2016, NLM changed the indexing system so that publishers are able to directly correct typos and errors in PubMed indexed articles.

PubMed has been reported to include some articles published in predatory journals. MEDLINE and PubMed policies for the selection of journals for database inclusion are slightly different. Weaknesses in the criteria and procedures for indexing journals in PubMed Central may allow publications from predatory journals to leak into PubMed.

Abstract

Hepatoblastoma is the most common primary malignant hepatic tumor of infancy and childhood, occurring predominantly in the first two years of life. The management of hepatoblastoma has changed markedly over the last 3 decades; neoadjuvant chemotherapy is now standard, particularly in unresectable tumors resulting in considerable preoperative tumor shrinkage and sometimes near total ablation of the tumor. A 20 month old infant was incidentally found to have a 7.6cm right sided retroperitoneal tumor on routine screening ultrasonography for left ureteral stenosis. Serum alpha fetoprotein was elevated. Biopsy revealed hepatoblastoma, mixed epithelial and embryonal type without mesenchymal elements. He underwent neoadjuvant chemotherapy. Although the tumor had decreased considerably in size, close proximity to major vascular structures precluded safe resection. Liver transplantation was performed; the explanted liver showed complete tumor necrosis with no residual malignancy. The postoperative course was uncomplicated and he is continuing on sixth cycle of chemotherapy.

How to access TOXNET information

Comprehensive Toxicology Information	Help for HSDB Users in PubChem (PDF) Help for HSDB Users in PubChem (Web Page) Video Tutorial
Toxicology Literature	Help for TOXLINE Users in PubMed (PDF) Help for TOXLINE Users in PubMed (Web Page)
Breastfeeding & Drugs	Help for LactMed Users in Bookshelf (PDF)Help for LactMed Users in Bookshelf (Web Page)
Chemical Information	Help for ChemIDplus Users in PubChem (PDF) Help for ChemIDplus Users in PubChem (Web Page)
Developmental Toxicology Literature	Help for DART Users in PubMed (PDF) Help for DART Users in PubMed (Web Page)
Drug-Induced Liver Injury	LiverTox in Bookshelf LiverTox has been migrated to BookShelf
Chemical Releases & Mapping	TOXMAP was retired. Underlying data remains accessible through their original resources: Government of Canada National Pollutant Release Inventory (NPRI), U.S. Census Bureau, U.S. EPA Clean Air Markets Program, U.S. EPA Geospatial Applications, U.S. EPA Facilities Registry System (FRS) , U.S. EPA Superfund Program, U.S. EPA Toxics Release Program (TRI), U.S. NIH NCI Surveillance, Epidemiology, and End Results Program (SEER), U.S. Nuclear Regulatory Commission (NRC) GIS application users can overlay the data in their own GIS applications.
Comparative Toxicogenomics	TOXNET’s CTD was retired. Visit CTD at NC State University.
Household Product Safety	The content of HPD is available from the original content provider Consumer Product Information Database https://www.whatsinproducts.com/
Occupational Exposure To Chemicals	HazMap was retired. The content of Haz-Map is still provided by the original content provider
Dietary Supplement Information	Dietary Supplement Ingredient Database (DSID): The Dietary Supplement Ingredient Database (DSID) (https://dsid.od.nih.gov) provides estimated levels of ingredients in dietary supplement products sold in the United States. These statistically predicted estimates may differ from labeled amounts and are based on chemical analysis of nationally representative products. This site is now being updated and maintained for access by the NIH Office of Dietary Supplements Dietary Supplement Label Database (DSLD): The Dietary Supplement Label Database (DSLD) (https://dsld.od.nih.gov) includes full label derived information from dietary supplement products marketed in the U.S. with a Web-based user interface that provides ready access to label information. This site is now being updated and maintained for access by the NIH Office of Dietary Supplements
Risk Assessment	TOXNET’s IRIS was retired. Visit IRIS at EPA. TOXNET ITER: The content of ITER will be available from the original content provider Toxicology Excellence for Risk Assessment Database http://www.iter.tera.org/
Animal Testing Alternatives	ALTBIB
Archived, No Longer Updated	Help for CCRIS Users in PubChem (PDF) Help for CCRIS Users in PubChem (Web Page) CPDB was retired. Access CPDB data at https://www.toxinfo.io and from the EPA at https://www.epa.gov/chemical-research/distributed-structure-searchable-toxicity-dsstox-database Help for GENE-TOX Users in PubChem (PDF)Help for GENE-TOX Users in PubChem (Web Page)

Archived Publications

2014 DailyMed/RxNorm Jamboree Workshop Last updated: September 29, 2014
2015 DailyMed/RxNorm Jamboree Workshop Last updated: October 14, 2015
2016 DailyMed/RxNorm Jamboree Workshop Last updated: November 11, 2018
2017 DailyMed/RxNorm Jamboree Workshop Last updated: November 11, 2018
Alphabetic Listing of MeSH Last updated: December 6, 2016
Changed Descriptors — 2015 Last updated: October 30, 2018
Changes in ASCII MeSH Format Last updated: April 9, 2016
Deleted Descriptors — 2018 Last updated: January 6, 2017
Files Available to Download Last updated: November 29, 2018
MeSH Qualifiers with Scope Notes Last updated: June 13, 2017
MeSH Staff Presentations and Publications Last updated: June 22, 2016
MeSH Staff Presentations and Publications (Archive) Last updated: April 24, 2013
SPL/DailyMed Jamboree Workshop 2013 Last updated: December 3, 2016
Use of Medical Subject Headings For Cataloging Last updated: October 29, 2019

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Simple NCBI Directory

NCBI Education
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PubMed
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BLAST

A tool that finds regions of similarity between biological sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance.
GenBank

A database of nucleotide sequences.
Molecular Structure and Function

A database of macromolecular 3D structures, as well as tools for their visualization and comparative analysis.
Taxonomy Database

A database of taxonomic names of lineages of organisms represented in NCBI’s sequence databases.
Conserved Domain Database (CDD)

A database to identify the conserved domains present in a protein sequence.
Reference Sequences (RefSeq)

A collection of reference sequences for genomes, gene transcripts, and proteins.
Vector Alignment Search Tool (VAST)

A computer algorithm developed at NCBI and used to identify similar protein 3-dimensional structures («similar structures») by purely geometric criteria and to identify distant homologs that cannot be recognized by sequence comparison.

Health Data Standards and Natural Language Processing

Health Information Technology and Health Data Standards at NLM

Clinical vocabulary standards and tools that support implementation of Meaningful Use, C-CDA, and other programs

Human Genome Resources

Online Mendelian Inheritance in Man (OMIM)

A guide to genes and inherited disorders.
Gene

Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
Genome Data Viewer

A genome browser supporting the exploration and analysis of more than 580 eukaryotic RefSeq genome assemblies.
More Human Genome resources at NCBI

Toxicology and Environmental Health

Toxicology and Environmental Health Information Program

Comprehensive toxicology and environmental health information.

Research Overview

The research program in the Computational Biology Branch is carried out by Senior Investigators, tenure track Investigators, Staff Scientists, Postdoctoral Fellows, and students. The program focuses on theoretical, analytical and applied approaches to a broad range of fundamental problems in molecular biology.

The expertise of the group is concentrated in sequence analysis, protein structure/function analysis, chemical informatics, and genome analysis. Research interests further cover a wide range of topics in computational biology and information science. These include, but are not limited to, database searching algorithms, sequence signal identification, mathematical models of evolution, statistical methods in virology, dynamic behavior of chemical reaction systems, statistical text-retrieval algorithms, protein structure and function prediction, comparative genomics, taxonomic trees, population genetics, and systems biology.

Many of the basic research projects conducted by CBB investigators serve to enhance and strengthen NCBI’s suite of publicly available databases and software application tools. Collaborative research efforts, among NCBI investigators as well as with the external research community, have led to the development of innovative algorithms (BLAST, PSI-BLAST, VAST, and COGs), novel research approaches (text neighboring) and fundamental resources (PubChem and CDD) that have transformed the field of computational biology. Algorithms and applications currently under development have the potential to further advance scientific discovery.

Members of the CBB contribute significantly to the validity and reliability of NCBI’s online resources by reviewing the quality and accuracy of the data deposited in the databases, as well as the accuracy of the information used to annotate the data. Members also provide leadership and guidance to the extramural community by planning and organizing scientific consortia to determine the most effective use of public sequence resources for large-scale or high-throughput experimental biology. Researchers collaborate to define new areas of research and identify appropriate computational mechanisms to address them.

Simple NCBI Directory

NCBI Education
NCBI Help Manual
NCBI Handbook
Training & Tutorials
Submit Data

Chemicals & Bioassays
Data & Software
DNA & RNA
Domains & Structures
Genes & Expression
Genetics & Medicine
Genomes & Maps
Homology
Literature
Proteins
Sequence Analysis
Taxonomy
Variation

PubMed
Bookshelf
PubMed Central
BLAST
Nucleotide
Genome
SNP
Gene
Protein
PubChem

Genetic Testing Registry
GenBank
Reference Sequences
Gene Expression Omnibus
Genome Data Viewer
Human Genome
Mouse Genome
Influenza Virus
Primer-BLAST
Sequence Read Archive

About NCBI
Research at NCBI
NCBI News & Blog
NCBI FTP Site
NCBI on Facebook
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NCBI on YouTube
Privacy Policy

Cited by 248 articles

Longer incubation period of coronavirus disease 2019 (COVID-19) in older adults.

Kong TK.
Kong TK.
Version 2. Aging Med (Milton). 2020 May 22;3(2):102-109. doi: 10.1002/agm2.12114. eCollection 2020 Jun.
Aging Med (Milton). 2020.

PMID: 32661509
Free PMC article.
Re-positive Cases of Nucleic Acid Tests in Discharged Patients With COVID-19: A Follow-Up Study.

Qiao XM, Xu XF, Zi H, Liu GX, Li BH, Du X, Tian ZH, Liu XY, Luo LS, Wang X.
Qiao XM, et al.
Front Med (Lausanne). 2020 Jun 23;7:349. doi: 10.3389/fmed.2020.00349. eCollection 2020.
Front Med (Lausanne). 2020.

PMID: 32656223
Free PMC article.
The Anatomic Pathology laboratory adjustments in the era of COVID-19 pandemic: The experience of a laboratory in a Portuguese central hospital.

Lamas NJ, Esteves S, Alves JR, Costa FE, Tente D, Fonseca P, Vizcaíno JR.
Lamas NJ, et al.
Ann Diagn Pathol. 2020 Jul 1;48:151560. doi: 10.1016/j.anndiagpath.2020.151560. Online ahead of print.
Ann Diagn Pathol. 2020.

PMID: 32645559
Free PMC article.
The experience of women infected by the COVID-19 during pregnancy in Brazil: a qualitative study protocol.

Freitas-Jesus JV, Rodrigues L, Surita FG.
Freitas-Jesus JV, et al.
Version 2. Reprod Health. 2020 Jul 8;17(1):108. doi: 10.1186/s12978-020-00958-z.
Reprod Health. 2020.

PMID: 32641133
Free PMC article.
Chopping the tail: how preventing superspreading can help to maintain COVID-19 control.

Kain MP, Childs ML, Becker AD, Mordecai EA.
Kain MP, et al.
medRxiv. 2020 Jul 3:2020.06.30.20143115. doi: 10.1101/2020.06.30.20143115. Preprint.
medRxiv. 2020.

PMID: 32637966
Free PMC article.

Выводы

Чему можно доверять:

сайту Министерства здравоохранения Российской Федерации (стандартам оказания медицинской помощи и критериям оценки качества оказания медицинской помощи);
клиническим рекомендациям Министерства здравоохранения Российской Федерации;
сайтам с инструкциями к лекарственным препаратам (Vidal, РЛС, «ЛС ГЭОТАР»);
электронным медицинским базам данных;
сайтам ВОЗ и Роспотребнадзора.

Чего лучше избегать:

обсуждений на форумах;
статей в «Википедии»;
рекламных материалов;
публикаций без ссылок на источники доказательной медицины.

Искать информацию о здоровье можно и нужно — но только на «правильных» сайтах с достоверными данными. И конечно, всегда помните, что врач в лечении ориентируется не только на стандарты и критерии качества, но и на свой опыт и особенности пациента.

Как искать в интернете достоверную медицинскую информацию

Similar articles

Alternative interfaces

Cited by 9 articles

Data mining of PubMed

What’s New

Cited by 8 articles

Similar articles

Content

Abstract

How to access TOXNET information

Archived Publications

Similar articles

Skip registration by using a 3rd party sign in option

Simple NCBI Directory

Biomedical Topics

Computational Molecular Biology

Health Data Standards and Natural Language Processing

Human Genome Resources

Toxicology and Environmental Health

Research Overview

Simple NCBI Directory

Cited by 248 articles

Выводы

Чему можно доверять:

Чего лучше избегать: